Lattice-free models of directed cell motility
نویسندگان
چکیده
منابع مشابه
Directed loop updates for quantum lattice models.
This article outlines how the quantum Monte Carlo directed loop update recently introduced can be applied to a wide class of quantum lattice models. Several models are considered: spin-s XXZ models with longitudinal and transverse magnetic fields, boson models with two-body interactions, and one-dimensional spinful fermion models. Expressions are given for the parameter regimes where very effic...
متن کاملModels of collective cell behaviour with crowding effects: comparing lattice-based and lattice-free approaches.
Individual-based models describing the migration and proliferation of a population of cells frequently restrict the cells to a predefined lattice. An implicit assumption of this type of lattice-based model is that a proliferative population will always eventually fill the lattice. Here, we develop a new lattice-free individual-based model that incorporates cell-to-cell crowding effects. We also...
متن کاملMinimal model of directed cell motility on patterned substrates.
Crawling cell motility is vital to many biological processes such as wound healing and the immune response. Using a minimal model we investigate the effects of patterned substrate adhesiveness and biophysical cell parameters on the direction of cell motion. We show that cells with low adhesion site formation rates may move perpendicular to adhesive stripes while those with high adhesion site fo...
متن کاملRNA-directed epigenetic silencing of Periostin inhibits cell motility
The over-expression of Periostin, a member of the fasciclin family of proteins, has been reported in a number of cancers and, in particular, in metastatic tumours. These include breast, ovarian, lung, colon, head and neck, pancreatic, prostate, neuroblastoma and thyroid cancers. It is thought that Periostin plays a major role in the development of metastases owing to its apparent involvement in...
متن کاملPhysical models of collective cell motility: from cell to tissue.
In this article, we review physics-based models of collective cell motility. We discuss a range of techniques at different scales, ranging from models that represent cells as simple self-propelled particles to phase field models that can represent a cell's shape and dynamics in great detail. We also extensively review the ways in which cells within a tissue choose their direction, the statistic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Physica A: Statistical Mechanics and its Applications
سال: 2016
ISSN: 0378-4371
DOI: 10.1016/j.physa.2015.08.049